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Contributed by Dr. Damian Rodriguez, DHSc, MS

Article at a Glance

With all of the excitement around Copaiba, you may have heard of beta-caryophyllene. But did you know that beta-caryophyllene can also be found in Black Pepper, Clove, Melissa, and Rosemary essential oils? Keep reading to learn about the benefits behind this powerful constituent.

What Is Beta-Caryophyllene?

Beta-caryophyllene is a bicyclic sesquiterpene. A sesquiterpene is made up of 15 carbon atoms and 24 hydrogen atoms. Sesquiterpenes can have a straight chain backbone, one ring, or, as is the case for beta-caryophyllene, two rings. This is why beta-caryophyllene is considered bicyclic. (To learn more, check out the doTERRA Chemistry Handbook.)

Benefits of Beta-Caryophyllene

While there’s still much to be learned about beta-caryophyllene, scientific research has discovered some great potential benefits.

Internal Use:

  • May support healthy nervous system based on experimental research.*8
  • May help support the cardiovascular system based on experimental research.*1-2
  • May support the digestive system based on experimental research.*5-6
  • In vivo research has shown that oral administration of beta-caryophyllene may support a healthy inflammatory and immune system response.*9

Topical Use:

  • May have cleansing properties based on experimental research.3-4
  • May help maintain youthful-looking skin based on experimental research.7

Using Beta-Caryophyllene

Given the variety of benefits beta-caryophyllene has to offer, you may be wondering how to add this powerful natural compound to your routine. Check out the list below for some possible ideas.

  • Take Copaiba Softgels in the morning.
  • Add Black Pepper or Rosemary to your favorite chicken recipe.
  • Add a few drops of Melissa to your face lotion.
  • Put a few drops of Copaiba essential oil in your DIY cleaner.

Beta-Caryophyllene in Your Life

As one of the main chemical constituents in many essential oils, beta-caryophyllene has a lot to offer. Whether you’re looking for some added cardiovascular support* or wanting to boost the cleansing power of your homemade cleaner, beta-caryophyllene has you covered. What is your favorite way to use beta-caryophyllene? 


doTERRA science blog articles are based on a variety of scientific sources. Many of the referenced studies are preliminary and further research is needed to gain greater understanding of the findings. Some articles offer multiple views on general health topics and are not the official position of doTERRA. Consult your healthcare provider before making changes to diet or exercise.

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