Essential Oil Mouthwash Trials


Even if you are not a regular user of essential oils, you are likely using them every day, as the benefits of essential oils and their terpene constituents have a long history of use in countless hygiene products. Due to their amazing health-benefitting properties, essential oils are common active ingredients in your skin care, hair care, cleaning, and even oral care products. When used appropriately, there is evidence that some essential oils may help keep the mouth, gums, and teeth clean and help brighten teeth for a healthy appearing smile, making them popular additions to the ingredient list of mouthwashes. A recent meta-analysis analyzed the effectiveness of essential oils as a component in mouthwash.

Meta-Analysis of Essential Oil Mouthwash

The Scottish University of Dundee is one of the United Kingdom’s leading universities, especially in dental research. Researchers from the Centre for Evidence-based Dentistry (CEBD) at Dundee recently published a meta-analysis on clinical trials of essential oil mouthwashes in base solutions containing both water and ethanol. The review included data from 16 trials and 4,016 patients. 14 of the 16 studies showed statistically significant differences between the trial groups and the placebo.1

Four of the studies actually measured two of the most significant indicators of poor oral hygiene2 and found both to be significantly lower in patients using essential oil mouthwashes compared to patients using mouthwashes containing cetylpyridinium chloride (CPC), the active ingredient commonly found in many brands of mouthwash.1 The data from these trials indicates that using mouthwash consisting of essential oil in ethanol solution after toothbrushing is more effective at promoting oral hygiene than toothbrushing alone or even using CPC-containing mouthwash after brushing one’s teeth.


Using mouthwash that contains essential oils after you brush your teeth is a natural way to keep your mouth clean and healthy. The results from this study support the use of essential oils in dental hygiene products, especially mouthwash. Try adding a drop or two of your favorite cleansing essential oils to your mouthwash or use doTERRA On Guard® Mouthwash after every brush to support oral health and maintain that bright smile. 



doTERRA Science blog articles are based on a variety of scientific sources. Many of the referenced studies are preliminary, experimental studies and further research is needed to gain a greater understanding of the findings. Essential oils may have drug interactions, patient contraindications, or adverse effects that cannot be evaluated using experimental research results alone. If you are interested in using essential oils for any health concern, consult with your healthcare provider first.

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